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Department of Bioscience and Biotechnology (DBB)

This department that offers bachelor, master, and doctoral degrees was born in 2013 after combing the Graduate Institute of Bioscience and Biotechnology established in 1993 and the Department of Life Sciences established in 2005. After finishing their base courses on chemistry, physics, biology and biostatistics, undergraduate students may explore all fields of Bioscience at molecular, cellular, physiological, and evolutionary levels by taking a group of well-designed advanced courses, including lecture and laboratory training according to their own interests.
DBB requires students to actively engage in research by conducting independent research projects at a laboratory of their choices. Students are also required to join training seminars to increase their ability to present their thoughts.

Before earning their master or doctoral degrees,graduate students must conduct intensive independent research within the following four programs.

Molecular and cellular biology: This program is concentrated on immune cell activation, apoptosis and gene therapy, stem cell culturing and relevant applications, cancer, neuron-degeneration, metabolic diseases and inflammation. Research findings have been published in prestigious journals such as Transgenic Research.

Developmental biology: This program is focused on hypoxia, gene regulation, signal transduction and carcinogenesis, animal embryonic developments, transgenic fish model systems, and reproductive physiology. Research findings have been published in esteemed journals such as Cell Death and Development and Development Dynamics, and Molecular Carcinogenesis.

Chemical biology: This program is centered on cellular-methylation and DNA-repair mechanisms, biological anti-oxidation systems, environmental analytical chemistry, nano-biotechnology, and biomedical materials. Research findings have been published in distinguished journals such as Biosensors and Bioelectronics,Journal of Nanomaterials Aquatic Toxiciology,Toxicology and Applied pharmacology and Free Radical Biology andMedicine.

Functional genomics and proteomics: This program is concentrated on protein engineering, bioinformatics, gene regulation systems, molecular evolution, and bio-resource development. Research findings have been published in reputable journals such as theJournal of Proteome ResearchPlos One, and Briefing in Bioinformatics.

DBB graduate students have applied their multi-disciplinary learning and research abilities in the Center of Excellence for the Oceans (formerly Center of Excellence for Marine Bioscience and Biotechnology,CMBB), the Molecular Integrative Biology (MIB) program operated between NTOU at the Institute of Cellular and Organismic Biology at Academia Sinica in Taiwan. Therefore, the DBB is involved in the transfer of state-of-the-art biotechnology not only for marine and aquaculture research but also for technological innovations that can lead to further insights in all of the life sciences. By participating in project-oriented and hypothesis-driven experiments, students can hone their unique abilities and prepare themselves to become leaders in the bio-industry or academia.
The DBB has been awarded a research excellence fund by the Center of Excellence for the Oceans for 6 years has been actively conducting a study on environmental adaptation under the umbrella of global environmental change. The DBB will continue to provide crucial contributions in these fields to solve contemporary challenges by conducting high-level research and by teaching.
Schematic representation of the reversible inhibitory function of TBA15pc/TBA29pc-P8T15-antibody-conjugated gold nanoparticles (Ab-Au NPs) by using irradiation of near-UV light
The schematic representation of (a) the preparation of antibody-conjugated gold nanoparticles (Ab-Au NPs), and (b) their use in the analysis of bacteria by employing laser desorption/ionization mass spectrometry (LDI-MS)
Predicted protein 3D structure of BIChi4G419 using a (PS) 2 server: A. secondary structure; B. molecular surface
Zebrafish hsc70 and hsp70 expression and heat shock effect dectected by whole mount in situ hybridization.
We re-discovered the biological meaning of protein-interaction networks by annotating the protein interaction motif, using the molecular function of each node in the network 
A tour of DBB representatives to a biotechnology corporation in Taiwan.